OAK RIDGE NATIONAL LAB HIGHLIGHTS OUR WORK ON GLOBAL GENOME REPAIR

Pre-incision complex in global genome repair

Oak Ridge National Lab highlights our work on the mechanisms of global genome nucleotide excision repair: “Summit Supercomputer Draws Molecular Blueprint for Repairing Damaged DNA”.

Related articles:

Yu, J., Yan, C., Paul, T. et al. Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair. Nat Commun 15, 8511 (2024).

Yu, J., Yan, C., Dodd, T. et al. Dynamic conformational switching underlies TFIIH function in transcription and DNA repair and impacts genetic diseases. Nat Commun 14, 2758 (2023).