Congratulations to Chunli Yan, Tom Dodd and Jina Yu who are co-authors on a just accepted paper in the journal Nature Communications. The paper is entitled “Mechanism of Rad26-assisted rescue of stalled RNA polymerase II in transcription-coupled repair.” Our integrative modeling study elucidates the mechanism by which Cockayne Syndrome B protein (CSB) binds to lesion-arrested RNA Polymerase II and assists its progression past sites of DNA damage during the early stages of transcription-coupled nucleotide excision repair (TC-NER). Our study also sheds light on the link between the positioning and dynamics of recognized CSB disease mutations, impacting understanding of the etiology of the severe genetic disorder Cockayne Syndrome.